HSD17B11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSD17B11 mutation is significantly associated with the RNA expression of many other genes, with 1,818 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD17B11-associated genes across cancer lineages are OR51N1P, LINC00314, and OR4Q3. Each is linked with HSD17B11 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B11-to-partner and partner-to-HSD17B11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B11→partner) and Y-score (partner→HSD17B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCOR51N1P →+0.015+4.020<.001.00931
CESCLINC00314 →+0.035+4.254<.001.00131
CESCOR4Q3 →+0.025+5.263<.001.00131
CESCRNA5SP307 →+0.119+4.020<.001.00931
CESCRNU6-183P →+0.178+4.247<.001.00731
CESCRNA5SP329 →+0.167+4.020<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,818 associations by consensus.

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