HLA-DQB2

Across TCGA cell cohorts, HLA-DQB2 RNA expression is significantly associated with the RNA expression of many other genes, with 1,687 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HLA-DQB2-associated genes across cancer lineages are HLA-DQA2, HLA-DQB1, and HLA-DRB1. Each is linked with HLA-DQB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HLA-DQB2-to-partner and partner-to-HLA-DQB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HLA-DQB2 versus HLA-DQA2 in BLOOD_Lymphoma, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DQB2→partner) and Y-score (partner→HLA-DQB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HLA-DQA2 →	+3.364	+2.244	<.001	<.001	3	8
BLOOD_Myeloma	HLA-DQB1 →	+3.698	+2.247	<.001	<.001	3	8
BLOOD_Myeloma	HLA-DRB1 →	+7.226	+2.901	<.001	<.001	3	6
BLOOD_Myeloma	HLA-DQA1 →	+6.413	+3.085	<.001	<.001	3	6
BLOOD_Myeloma	HLA-DRB5 →	+4.625	+2.572	<.001	<.001	3	6
BLOOD_Leukemia	HLA-DOA →	+2.520	+1.174	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,687 associations by consensus.

HLA-DQB2 vs HLA-DQA2 — BLOOD_Lymphoma

Explore this scatter interactively →