HAND2-AS1

Across TCGA patient cohorts, HAND2-AS1 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAND2-AS1-associated genes across cancer lineages are RN7SL596P, RN7SL592P, and RNU6-87P. Each is linked with HAND2-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAND2-AS1-to-partner and partner-to-HAND2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL596P grouped by HAND2-AS1-low versus HAND2-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAND2-AS1→partner) and Y-score (partner→HAND2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL596P →	+0.213	+3.156	.006	.006	3	1
UCEC	RN7SL592P →	+0.355	+3.860	<.001	.001	3	1
UCEC	RNU6-87P →	+0.764	+3.046	.001	.008	3	1
UCEC	RN7SL248P →	+0.118	+4.400	<.001	.006	3	1
UCEC	RNVU1-19 →	+0.923	+3.692	<.001	.007	3	1
UCEC	MRPL57P3 →	+0.586	+3.761	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

RN7SL596P by HAND2-AS1 expression — UCEC

Explore this box plot interactively →