H1-7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H1-7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,565 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H1-7-associated proteins across cancer lineages are TOP2A_S1106, PSMD2, and NCAPG_S973. Each is linked with H1-7 in more than 2 cancer types. Because this analysis shows association rather than direction, both H1-7-to-partner and partner-to-H1-7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-7→partner) and Y-score (partner→H1-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADTOP2A_S1106 →-0.685-0.248<.001.00433
GBMPSMD2 →-0.212-0.375<.001<.00133
GBMNCAPG_S973 →-0.947-0.383<.001<.00133
GBMNUF2 →-0.730-0.442<.001<.00133
GBMNUF2_S247 →-0.946-0.377<.001.00133
LSCCPBK →-0.544-0.265.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,565 associations by consensus.

Exploration