GTF2A1L

Across TCGA patient cohorts, GTF2A1L mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2A1L-associated genes across cancer lineages are MIR4507, MIR548AL, and GAGE12J. Each is linked with GTF2A1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2A1L-to-partner and partner-to-GTF2A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4507 grouped by GTF2A1L-low versus GTF2A1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2A1L→partner) and Y-score (partner→GTF2A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4507 →	+0.687	+5.420	<.001	.005	3	1
UCEC	MIR548AL →	+0.773	+6.226	<.001	.001	3	1
UCEC	GAGE12J →	+0.879	+5.186	<.001	.007	3	1
UCEC	DANT1 →	+0.294	+4.982	.002	.009	3	1
UCEC	CDY7P →	+0.045	+5.358	.001	.006	3	1
UCEC	RN7SL340P →	+0.333	+6.226	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MIR4507 by GTF2A1L expression — UCEC

Explore this box plot interactively →