GPR83

Across TCGA patient cohorts, GPR83 mutation is significantly associated with the RNA expression of many other genes, with 1,523 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR83-associated genes across cancer lineages are USP12PY, OR56A7P, and RN7SL810P. Each is linked with GPR83 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR83-to-partner and partner-to-GPR83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP12PY grouped by GPR83-low versus GPR83-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR83→partner) and Y-score (partner→GPR83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	USP12PY →	+0.044	+5.647	<.001	.004	3	3
GBM	OR56A7P →	+0.087	+6.614	<.001	<.001	3	2
GBM	RN7SL810P →	+0.246	+4.969	.001	.009	3	2
HNSC	RNA5SP113 →	+0.251	+4.754	<.001	.005	3	2
BRCA	RNU6-1258P →	+0.150	+7.471	<.001	.008	3	2
BLCA	NANOGP9 →	+0.090	+5.329	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,523 associations by consensus.

USP12PY by GPR83 expression — LIHC

Explore this box plot interactively →