RNU6-1258P

associated omics data
RNA, U6 small nuclear 1258, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-1258P profile across patient tissues and cancer cell-line models. RNU6-1258P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, RNU6-1258P RNA expression shows 9,260 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight COAD, and LUSC as cancer lineages where RNU6-1258P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-1258P survival associations across molecular data types. RNU6-1258P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-1258P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier7COAD (108)view →
This table ranks reproducible RNU6-1258P RNA expression–survival associations across cancer types. High RNU6-1258P expression shows unfavorable associations in COAD, HNSC, KIRC, BRCA, BLCA and STAD. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU6-1258P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSTertileAll0.1420.871<.001108view →
HNSCOSTertileIV0.2300.608.00690view →
KIRCDFSTertileIV0.1270.619.00878view →
BRCADFSTertileAll0.1190.527<.00136view →
BLCAOSTertileIII,IV0.1880.654.01527view →
STADDFSTertileAll0.4840.667.02521view →
Pink = unfavorable, green = favorable. all 7 lineages →

RNU6-1258P-COAD (OS)

Kaplan–Meier survival curve for RNU6-1258P RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-1258P in patient tissues and cancer cell lines. In patient samples, RNU6-1258P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA9,260LUSC (4458)view →
Protein (mass-spec)5,886GBM (2921)view →