RNU6-1258P

Across TCGA pan-cancer cohorts, RNU6-1258P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-1258P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU6-1258P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1258P expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

COAD, HNSC, and KIRC are the cancer types where RNU6-1258P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.142	0.871	<.001	108	view →
HNSC	OS	Tertile	IV	0.230	0.608	.006	90	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	78	view →
BRCA	DFS	Tertile	All	0.119	0.527	<.001	36	view →
BLCA	OS	Tertile	III,IV	0.188	0.654	.015	27	view →
STAD	DFS	Tertile	All	0.484	0.667	.025	21	view →
LGG	DFS	Tertile	All	0.859	0.378	.046	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-1258P–COAD (OS)

Open the COAD breakdown →