GPR160

Across TCGA patient cohorts, GPR160 mutation is significantly associated with the RNA expression of many other genes, with 1,105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR160-associated genes across cancer lineages are USP12PY, RNU6-491P, and LINC01957. Each is linked with GPR160 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR160-to-partner and partner-to-GPR160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP12PY grouped by GPR160-low versus GPR160-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR160→partner) and Y-score (partner→GPR160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	USP12PY →	+0.093	+5.685	<.001	.003	3	2
BRCA	RNU6-491P →	+0.323	+8.055	<.001	.007	3	2
LUAD	LINC01957 →	+0.074	+7.930	<.001	.008	3	2
UCEC	MIR132 →	+0.345	+3.186	<.001	.006	3	2
BRCA	SPDYE8 →	+0.014	+8.471	<.001	.005	3	1
LIHC	LCE2C →	+0.209	+5.355	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

USP12PY by GPR160 expression — BLCA

Explore this box plot interactively →