RNU6-491P

Q-omics provides the consensus-scored RNU6-491P profile across patient tissues and cancer cell-line models. RNU6-491P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, RNU6-491P RNA expression shows 7,439 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight ESCA, and COAD as cancer lineages where RNU6-491P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-491P survival associations across molecular data types. RNU6-491P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-491P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	LUAD (54)	view →

This table ranks reproducible RNU6-491P RNA expression–survival associations across cancer types. High RNU6-491P expression shows unfavorable associations in ESCA, LUAD, LUSC, LGG, KIRC and SARC. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for RNU6-491P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	III,IV	0.100	0.442	.003	54	view →
LUAD	OS	Tertile	All	0.161	0.788	.001	54	view →
LUSC	DFS	Tertile	All	0.139	0.707	.022	27	view →
LGG	DFS	Tertile	All	0.410	0.749	<.001	21	view →
KIRC	DFS	Tertile	All	0.147	0.630	.005	18	view →
SARC	OS	Tertile	All	0.156	0.767	.001	15	view →

Pink = unfavorable, green = favorable. all 7 lineages →

RNU6-491P-ESCA (DFS)

Explore this curve interactively →