RNU6-491P

Across TCGA pan-cancer cohorts, RNU6-491P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-491P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-491P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-491P expression acts as an unfavorable survival marker.

ESCA, LUAD, and LUSC are the cancer types where RNU6-491P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	III,IV	0.100	0.442	.003	54	view →
LUAD	OS	Tertile	All	0.161	0.788	.001	54	view →
LUSC	DFS	Tertile	All	0.139	0.707	.022	27	view →
LGG	DFS	Tertile	All	0.410	0.749	<.001	21	view →
KIRC	DFS	Tertile	All	0.147	0.630	.005	18	view →
SARC	OS	Tertile	All	0.156	0.767	.001	15	view →
GBM	OS	Tertile	All	0.240	0.419	.037	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-491P–ESCA (DFS)

Open the ESCA breakdown →