RNU6-491P

Across TCGA patient cohorts, RNU6-491P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,955 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-491P-associated GO terms across cancer lineages are Regulation of pattern recognition receptor signaling pathway, Glial cell differentiation, and Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with RNU6-491P in more than 5 cancer types. Because this analysis shows association rather than direction, both RNU6-491P-to-partner and partner-to-RNU6-491P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of pattern recognition receptor signaling pathway grouped by RNU6-491P-low versus RNU6-491P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-491P→partner) and Y-score (partner→RNU6-491P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of pattern recognition receptor signaling pathway →	+0.091	+0.163	<.001	<.001	3	6
STAD	Glial cell differentiation →	+0.079	+0.183	<.001	<.001	3	5
STAD	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.109	+0.173	<.001	<.001	3	5
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.119	+0.179	<.001	<.001	3	5
STAD	Activation of innate immune response →	+0.094	+0.181	<.001	<.001	3	5
STAD	Regulation of protein ubiquitination →	+0.122	+0.197	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,955 associations by consensus.

Regulation of pattern recognition receptor signaling pathway by RNU6-491P expression — STAD

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