GPR160

Across TCGA pan-cancer cohorts, GPR160 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated GPR160 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GPR160 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GPR160 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BLCA show a favorable association.

KIRC, ACC, and BLCA are the cancer types where GPR160 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.739	0.504	<.001	171	view →
ACC	DFS	Median	All	0.243	0.687	<.001	88	view →
BLCA	OS	Median	All	0.508	0.341	.003	65	view →
LUSC	OS	Median	All	0.828	0.719	<.001	62	view →
SKCM	OS	Median	All	0.393	0.228	<.001	36	view →
MESO	OS	Quartile	All	0.178	0.663	.006	33	view →
UVM	DFS	Median	III,IV	0.257	0.716	.002	32	view →
LGG	DFS	Tertile	All	0.668	0.801	.001	32	view →
ESCA	OS	Median	All	0.617	1.000	.009	27	view →
UCEC	DFS	Tertile	All	0.481	0.779	.004	24	view →
BRCA	OS	Median	IV	0.723	0.337	.009	20	view →
READ	DFS	Tertile	IV	0.282	0.758	.010	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

GPR160–KIRC (DFS)

Open the KIRC breakdown →