GAL3ST3

Across TCGA patient cohorts, GAL3ST3 mutation is significantly associated with the RNA expression of many other genes, with 1,501 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAL3ST3-associated genes across cancer lineages are RN7SKP153, USP9YP10, and SMCP. Each is linked with GAL3ST3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAL3ST3-to-partner and partner-to-GAL3ST3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP153 grouped by GAL3ST3-low versus GAL3ST3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL3ST3→partner) and Y-score (partner→GAL3ST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP153 →	+0.199	+5.516	.001	.004	3	3
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	2
LIHC	SMCP →	+0.067	+5.355	<.001	.005	3	2
UCEC	LINC02019 →	+0.452	+1.928	<.001	.009	3	2
UCEC	RN7SL248P →	+0.063	+3.307	<.001	.003	3	2
UCEC	ZUP1 →	+0.564	+2.447	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,501 associations by consensus.

RN7SKP153 by GAL3ST3 expression — COAD

Explore this box plot interactively →