FKBP1B

Across TCGA patient cohorts, FKBP1B mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP1B-associated genes across cancer lineages are MIR517B, RNU6-839P, and RNU6-1075P. Each is linked with FKBP1B in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP1B-to-partner and partner-to-FKBP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR517B grouped by FKBP1B-low versus FKBP1B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP1B→partner) and Y-score (partner→FKBP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR517B →	+0.611	+8.055	<.001	.007	3	2
SKCM	RNU6-839P →	+0.458	+7.816	<.001	.008	3	1
SKCM	RNU6-1075P →	+0.458	+7.816	<.001	.008	3	1
SKCM	SNORD115-22 →	+0.383	+7.816	<.001	.008	3	1
SKCM	SNORA35 →	+0.404	+7.816	<.001	.008	3	1
SKCM	PABPC1L2B-AS1 →	+0.034	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

MIR517B by FKBP1B expression — BRCA

Explore this box plot interactively →