Q-omics provides the consensus-scored SNORA35 profile across patient tissues and cancer cell-line models. SNORA35 expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, SNORA35 RNA expression shows 5,141 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, and STAD as cancer lineages where SNORA35 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SNORA35 survival associations across molecular data types. SNORA35 RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SNORA35 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	SKCM (9)	view →

This table ranks reproducible SNORA35 RNA expression–survival associations across cancer types. High SNORA35 expression shows unfavorable associations in SKCM, STAD and KIRC. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for SNORA35 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.046	0.728	<.001	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
KIRC	DFS	Tertile	All	0.283	0.637	.024	6	view →

Pink = unfavorable, green = favorable. all 3 lineages →

SNORA35-SKCM (DFS)

Kaplan–Meier survival curve for SNORA35 RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SNORA35 in patient tissues and cancer cell lines. In patient samples, SNORA35 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,141	STAD (4605)	view →
RNA	3,503	ESCA (1563)	view →