FBXO43

Across TCGA patient cohorts, FBXO43 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,493 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBXO43-associated proteins across cancer lineages are CDK1, FEN1, and RRM2. Each is linked with FBXO43 in more than 7 cancer types. Because this analysis shows association rather than direction, both FBXO43-to-partner and partner-to-FBXO43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO43 versus CDK1 in CCRCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO43→partner) and Y-score (partner→FBXO43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CDK1 →	+0.712	+0.346	<.001	<.001	3	8
OV	FEN1 →	+0.587	+0.823	<.001	<.001	3	8
OV	RRM2 →	+0.879	+0.848	<.001	<.001	3	8
GBM	SMC4 →	+0.590	+0.651	<.001	<.001	3	8
OV	MCM6 →	+0.857	+0.749	<.001	<.001	3	8
LSCC	TOP2A_S1106 →	+0.874	+0.503	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,493 associations by consensus.

FBXO43 vs CDK1 — CCRCC

Explore this scatter interactively →