FAM167A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM167A protein abundance is significantly associated with the RNA expression of many other genes, with 2,384 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM167A-associated genes across cancer lineages are RIMS3, EHD3, and L3MBTL4. Each is linked with FAM167A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM167A-to-partner and partner-to-FAM167A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM167A versus RIMS3 in UCEC, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM167A→partner) and Y-score (partner→FAM167A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRIMS3 →+1.976+2.153<.001.00132
UCECEHD3 →+1.839+1.692.005.00132
UCECL3MBTL4 →+3.469+2.153<.001.00132
UCECRNU6-460P →+2.696+1.314.002.00232
UCECRNU7-59P →+2.395+1.333.006.00132
GBMZDHHC2 →+0.703+0.476.003.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,384 associations by consensus.

FAM167A vs RIMS3 — UCEC

Per-sample scatter of FAM167A vs RIMS3 in UCEC (Pearson r = 0.83).

Explore this scatter interactively →

Exploration