RNA, U6 small nuclear 460, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-460P profile across patient tissues and cancer cell-line models. RNU6-460P expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, RNU6-460P is differentially expressed in 5, with the highest sampling consensus in LUSC. Additionally, RNU6-460P RNA expression shows 12,568 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight COAD, LUSC, and UVM as cancer lineages where RNU6-460P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-460P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-460P survival associations across molecular data types. RNU6-460P RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-460P RNA expression–survival associations across cancer types. High RNU6-460P expression shows unfavorable associations in COAD, STAD, MESO, ESCA and READ, but favorable associations in PAAD. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU6-460P RNA expression.
This table summarizes RNU6-460P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-460P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-460P shows lower tumor expression in LUSC, KICH and THCA and higher tumor expression in PAAD and CHOL. The LUSC box plot shows higher RNU6-460P RNA expression in normal versus tumor tissue (log2 FC = −0.382, t-test p < 0.001).
This table shows molecular features associated with RNU6-460P in patient tissues and cancer cell lines. In patient samples, RNU6-460P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
