FAM167A

Across TCGA pan-cancer cohorts, FAM167A RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of FAM167A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM167A RNA is repressed in tumor relative to normal tissue. In most cancer types FAM167A is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KIRP are the cancer types where FAM167A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM167A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−3.225	<.001	12	view →
THCA	All	IV	−5.345	<.001	11	view →
KIRP	Male	All	−1.926	<.001	11	view →
LUSC	Female	III,IV	−3.710	<.001	9	view →
LUAD	Female	III,IV	−2.517	<.001	9	view →
KICH	Female	II,III,IV	−3.550	<.001	8	view →
CHOL	All	All	+2.272	<.001	5	view →
BLCA	Male	III,IV	+0.994	.004	4	view →
COAD	All	All	+0.582	.003	4	view →
PRAD	All	All	−1.263	<.001	2	view →
STAD	Male	IV	−1.284	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

FAM167A–KIRC

Open the KIRC breakdown →