Across TCGA patient cohorts, DSCR4 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DSCR4-associated genes across cancer lineages are RNU4-58P, RNA5SP72, and SULT6B1. Each is linked with DSCR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DSCR4-to-partner and partner-to-DSCR4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCR4→partner) and Y-score (partner→DSCR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.566	+4.718	<.001	.001	3	2
UCEC	RNA5SP72 →	+0.641	+4.616	<.001	.001	3	2
SKCM	SULT6B1 →	+0.085	+2.621	<.001	.008	3	2
UCEC	RN7SL386P →	+0.226	+4.184	.002	.003	3	1
SKCM	SGO1P2 →	+0.038	+4.199	<.001	.001	3	1
SKCM	PPIAP27 →	+0.249	+2.968	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

DSCR4 survival (RNA) · tumor vs normal (RNA) · all DSCR4 data types