peptidylprolyl isomerase A pseudogene 27Genealiases: []
Q-omics provides the consensus-scored PPIAP27 profile across patient tissues and cancer cell-line models. PPIAP27 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, PPIAP27 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, PPIAP27 RNA expression shows 6,328 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, THCA, and STAD as cancer lineages where PPIAP27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP27 survival associations across molecular data types. PPIAP27 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP27 RNA expression–survival associations across cancer types. High PPIAP27 expression shows unfavorable associations in KICH, UCS, KIRC, STAD, CESC and MESO. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for PPIAP27 RNA expression.
This table summarizes PPIAP27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP27 shows lower tumor expression in THCA. The THCA box plot shows higher PPIAP27 RNA expression in normal versus tumor tissue (log2 FC = −0.089, t-test p = .020).
This table shows molecular features associated with PPIAP27 in patient tissues and cancer cell lines. In patient samples, PPIAP27 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
