PPIAP27

Across TCGA pan-cancer cohorts, PPIAP27 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated PPIAP27 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PPIAP27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPIAP27 expression acts as an unfavorable survival marker.

KICH, UCS, and KIRC are the cancer types where PPIAP27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
UCS	DFS	Tertile	III,IV	0.125	0.452	.003	72	view →
KIRC	DFS	Tertile	All	0.465	0.664	<.001	58	view →
STAD	DFS	Quartile	II,III,IV	0.473	0.776	<.001	42	view →
MESO	OS	Tertile	IV	0.155	0.624	.004	36	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
OV	OS	Tertile	IV	0.355	0.780	.001	18	view →
BLCA	DFS	Tertile	III,IV	0.198	0.301	.022	15	view →
ACC	OS	Tertile	All	0.645	0.886	.015	15	view →
SARC	OS	Tertile	All	0.321	0.741	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

PPIAP27–KICH (DFS)

Open the KICH breakdown →