PPIAP27

Across TCGA patient cohorts, PPIAP27 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,328 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP27-associated GO terms across cancer lineages are Cellular respiration, Ribosomal large subunit assembly, and Mitochondrial gene expression. Each is linked with PPIAP27 in more than 10 cancer types. Because this analysis shows association rather than direction, both PPIAP27-to-partner and partner-to-PPIAP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by PPIAP27-low versus PPIAP27-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP27→partner) and Y-score (partner→PPIAP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Cellular respiration →	+0.086	+0.026	<.001	.002	3	11
STAD	Ribosomal large subunit assembly →	+0.060	+0.398	<.001	<.001	3	11
LUSC	Mitochondrial gene expression →	+0.086	+0.027	<.001	.001	3	10
LUSC	Oxidative phosphorylation →	+0.093	+0.021	<.001	.002	2	10
LUSC	Aerobic respiration →	+0.087	+0.021	<.001	<.001	2	10
KIRP	rRNA base methylation →	+0.049	+0.094	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,328 associations by consensus.

Cellular respiration by PPIAP27 expression — LUSC

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