CYP4F27P

Across TCGA patient cohorts, CYP4F27P mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F27P-associated genes across cancer lineages are OR7E8P, MIR548AL, and MIR4449. Each is linked with CYP4F27P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F27P-to-partner and partner-to-CYP4F27P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E8P grouped by CYP4F27P-low versus CYP4F27P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F27P→partner) and Y-score (partner→CYP4F27P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR7E8P →	+0.139	+3.638	<.001	.006	3	1
UCEC	MIR548AL →	+0.287	+4.226	<.001	.008	3	1
UCEC	MIR4449 →	+0.969	+3.239	<.001	.009	3	1
UCEC	RNU6-511P →	+0.960	+4.470	<.001	<.001	3	1
UCEC	SNORD56B →	+0.684	+3.845	.005	.004	3	1
UCEC	RAP1BP3 →	+0.151	+3.453	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR7E8P by CYP4F27P expression — UCEC

Explore this box plot interactively →