CSTF3-DT

Across TCGA patient cohorts, CSTF3-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 10,770 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CSTF3-DT-associated proteins across cancer lineages are TPX2, SMC4, and TOP2A. Each is linked with CSTF3-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both CSTF3-DT-to-partner and partner-to-CSTF3-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTF3-DT versus TPX2 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF3-DT→partner) and Y-score (partner→CSTF3-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TPX2 →	+0.708	+0.171	<.001	.001	3	5
OV	SMC4 →	+0.647	+0.221	<.001	<.001	3	5
BRCA	TOP2A →	+0.700	+0.063	<.001	<.001	3	5
BRCA	TOP2A_S1213 →	+0.539	+0.070	<.001	.001	3	5
GBM	DNAJC9 →	+0.449	+0.303	<.001	<.001	3	5
GBM	TNKS1BP1 →	-0.278	-0.179	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,770 associations by consensus.

CSTF3-DT vs TPX2 — OV

Explore this scatter interactively →