CORO7-PAM16

Across TCGA patient cohorts, CORO7-PAM16 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CORO7-PAM16-associated genes across cancer lineages are MIR378D1, MIR4682, and RNU6-457P. Each is linked with CORO7-PAM16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO7-PAM16-to-partner and partner-to-CORO7-PAM16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR378D1 grouped by CORO7-PAM16-low versus CORO7-PAM16-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO7-PAM16→partner) and Y-score (partner→CORO7-PAM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR378D1 →	+0.547	+7.816	<.001	.008	3	2
UCEC	MIR4682 →	+0.472	+3.110	.003	.002	3	2
SKCM	RNU6-457P →	+0.328	+7.816	<.001	.008	3	2
BRCA	MIR6515 →	+0.717	+8.055	<.001	.007	3	1
UCEC	CICP28 →	+0.026	+3.029	.003	.005	3	1
SKCM	RNU6-518P →	+0.358	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

MIR378D1 by CORO7-PAM16 expression — SKCM

Explore this box plot interactively →