CORO7-PAM16

Across TCGA pan-cancer cohorts, CORO7-PAM16 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CORO7-PAM16’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CORO7-PAM16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CORO7-PAM16 is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.

KIRP, KIRC, and BLCA are the cancer types where CORO7-PAM16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CORO7-PAM16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	+0.075	<.001	9	view →
KIRC	All	All	+0.027	<.001	7	view →
BLCA	All	All	−0.048	.001	6	view →
LUSC	All	II,III,IV	−0.065	<.001	5	view →
LIHC	All	All	+0.013	.006	4	view →
UCEC	All	All	−0.041	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CORO7-PAM16–KIRP

Open the KIRP breakdown →