Q-omics provides the consensus-scored CICP28 profile across patient tissues and cancer cell-line models. CICP28 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, CICP28 is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, CICP28 RNA expression shows 8,919 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRP, KIRC, and TGCT as cancer lineages where CICP28 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CICP28 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CICP28 survival associations across molecular data types. CICP28 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CICP28 RNA expression–survival associations across cancer types. High CICP28 expression shows unfavorable associations in KIRP, HNSC, MESO, KICH and SKCM, but favorable associations in ESCA. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for CICP28 RNA expression.
This table summarizes CICP28 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for CICP28. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CICP28 shows lower tumor expression in KIRC. The KIRC box plot shows higher CICP28 RNA expression in normal versus tumor tissue (log2 FC = −0.004, t-test p = .005).
This table shows molecular features associated with CICP28 in patient tissues and cancer cell lines. In patient samples, CICP28 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
