CICP28

Across TCGA patient cohorts, CICP28 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,567 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CICP28-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of DNA repair, and Nucleotide-excision repair. Each is linked with CICP28 in more than 16 cancer types. Because this analysis shows association rather than direction, both CICP28-to-partner and partner-to-CICP28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by CICP28-low versus CICP28-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP28→partner) and Y-score (partner→CICP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA metabolic process →	+0.075	+0.046	<.001	<.001	3	17
ESCA	Regulation of DNA repair →	+0.078	+0.049	<.001	<.001	3	17
ESCA	Nucleotide-excision repair →	+0.056	+0.028	<.001	.001	3	16
ESCA	DNA-templated transcription initiation →	+0.065	+0.037	<.001	<.001	3	16
ESCA	Transcription initiation at RNA polymerase II promoter →	+0.074	+0.049	<.001	<.001	3	16
ESCA	Protein acylation →	+0.061	+0.037	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,567 associations by consensus.

Positive regulation of DNA metabolic process by CICP28 expression — ESCA

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