Q-omics provides the consensus-scored RNU6-457P profile across patient tissues and cancer cell-line models. RNU6-457P expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, RNU6-457P RNA expression shows 8,173 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight COAD, and GBM as cancer lineages where RNU6-457P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for RNU6-457P — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes RNU6-457P survival associations across molecular data types. RNU6-457P RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-457P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	COAD (90)	view →

This table ranks reproducible RNU6-457P RNA expression–survival associations across cancer types. High RNU6-457P expression shows unfavorable associations in COAD, KIRC, ESCA and BLCA, but favorable associations in STAD and LUAD. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU6-457P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.177	0.809	<.001	90	view →
KIRC	DFS	Tertile	IV	0.083	0.641	<.001	54	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
BLCA	DFS	Tertile	All	0.179	0.521	.019	36	view →
STAD	OS	Tertile	IV	1.000	0.313	.023	30	view →
LUAD	DFS	Tertile	All	0.939	0.655	.024	27	view →

Pink = unfavorable, green = favorable. all 8 lineages →

RNU6-457P-COAD (OS)

Kaplan–Meier survival curve for RNU6-457P RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-457P in patient tissues and cancer cell lines. In patient samples, RNU6-457P shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	8,173	GBM (7335)	view →
RNA	7,893	KIRC (1930)	view →