CNNM3-DT

Across TCGA patient cohorts, CNNM3-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 17,054 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNNM3-DT-associated proteins across cancer lineages are PHC3, SMC1A, and UPP1. Each is linked with CNNM3-DT in more than 6 cancer types. Because this analysis shows association rather than direction, both CNNM3-DT-to-partner and partner-to-CNNM3-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM3-DT versus PHC3 in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM3-DT→partner) and Y-score (partner→CNNM3-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PHC3 →	+0.422	+0.656	<.001	.001	3	7
BRCA	SMC1A →	+0.322	+0.853	<.001	<.001	3	7
HNSC	UPP1 →	-0.853	-0.756	<.001	.003	3	7
GBM	HCFC1 →	+0.249	+0.552	<.001	.001	3	7
HNSC	PDS5B →	+0.257	+0.939	<.001	<.001	3	6
GBM	ZNF638 →	+0.254	+0.557	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,054 associations by consensus.

CNNM3-DT vs PHC3 — BRCA

Explore this scatter interactively →