cilia and flagella associated protein 97Genealiases: KIAA1430 · hmw
Q-omics provides the consensus-scored CFAP97 profile across patient tissues and cancer cell-line models. CFAP97 expression is associated with patient survival in 26 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, CFAP97 is differentially expressed in 8, with the highest sampling consensus in COAD. Additionally, CFAP97 RNA expression shows 20,109 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, COAD, and THYM as cancer lineages where CFAP97 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CFAP97 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CFAP97 survival associations across molecular data types. CFAP97 RNA expression shows survival associations in the most cancer types (26), followed by mutation status (4) and mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CFAP97 RNA expression–survival associations across cancer types. High CFAP97 expression shows unfavorable associations in UVM, CESC, PAAD and LIHC, but favorable associations in KIRC and BRCA. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for CFAP97 RNA expression.
This table summarizes CFAP97 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8, while mass-spec protein shows differences in 4. The strongest signals are observed in COAD for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for CFAP97. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CFAP97 shows lower tumor expression in KICH and higher tumor expression in COAD, HNSC, KIRC, CHOL and LIHC. The COAD box plot shows higher CFAP97 RNA expression in tumor versus normal tissue (log2 FC = +0.947, t-test p < 0.001).
This table shows molecular features associated with CFAP97 in patient tissues and cancer cell lines. In patient samples, CFAP97 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, CFAP97 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_SCLC, while CRISPR and shRNA rows add functional-dependency signals in SKIN and LARGE_INTESTINE.
