CFAP97

Across TCGA patient cohorts, CFAP97 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP97-associated genes across cancer lineages are FoxM1, Notch1, and ATM. Each is linked with CFAP97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP97-to-partner and partner-to-CFAP97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by CFAP97-low versus CFAP97-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP97→partner) and Y-score (partner→CFAP97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.282	+2.415	.006	.003	3	2
UCEC	Notch1 →	+0.198	+1.906	<.001	.016	3	2
UCEC	ATM →	-0.576	-2.446	.001	.018	3	2
UCEC	Cyclin-E2 →	+0.176	+1.710	.009	.025	3	2
UCEC	EGFR_pY1068 →	-0.287	-2.584	.004	.010	3	1
UCEC	eIF4E →	+0.169	+3.183	.046	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

FoxM1 by CFAP97 expression — UCEC

Explore this box plot interactively →