Q-omics provides the consensus-scored CCNT1 profile across patient tissues and cancer cell-line models. CCNT1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, CCNT1 is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, CCNT1 protein abundance shows 30,706 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight ACC, HNSC, and LSCC as cancer lineages where CCNT1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CCNT1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CCNT1 survival associations across molecular data types. CCNT1 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (7) and mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CCNT1 RNA expression–survival associations across cancer types. High CCNT1 expression shows unfavorable associations in ACC, LIHC, UVM, MESO and CESC, but favorable associations in KIRC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for CCNT1 RNA expression.
This table summarizes CCNT1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 6. The strongest signals are observed in HNSC for RNA and COAD for protein.
This table ranks reproducible tumor–normal expression differences for CCNT1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CCNT1 shows lower tumor expression in THCA and higher tumor expression in HNSC, LIHC, CHOL, COAD and LUSC. The HNSC box plot shows higher CCNT1 RNA expression in tumor versus normal tissue (log2 FC = +0.738, t-test p < 0.001).
This table shows molecular features associated with CCNT1 in patient tissues and cancer cell lines. In patient samples, CCNT1 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, CCNT1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in SKIN and UPPER_AERODIGESTIVE_TRACT.
