CCNT1

Across TCGA cell cohorts, CCNT1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNT1-associated genes across cancer lineages are LY6G6F, S100A7A, and IFNL3. Each is linked with CCNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNT1-to-partner and partner-to-CCNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY6G6F grouped by CCNT1-low versus CCNT1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT1→partner) and Y-score (partner→CCNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	S100A7A →	+0.056	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	IFNL3 →	+0.100	+5.209	.001	.005	3	1
LARGE_INTESTINE	ARL13A →	+0.084	+3.369	<.001	.007	3	1
SKIN	OR2T4 →	+0.026	+5.415	<.001	.004	3	1
BLOOD_Leukemia	THEG →	+0.176	+4.354	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

LY6G6F by CCNT1 expression — URINARY_TRACT

Explore this box plot interactively →