CCNT1

Across TCGA pan-cancer cohorts, CCNT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCNT1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CCNT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCNT1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where CCNT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.666	0.910	.002	46	view →
PDAC	DFS	Median	IV	0.785	0.214	.006	10	view →
CCRCC	OS	Median	III,IV	0.771	0.987	.025	8	view →
LSCC	DFS	Quartile	II,III,IV	0.929	0.514	.018	3	view →
UCEC	DFS	Quartile	All	0.843	0.966	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCNT1–HNSC (DFS)

Open the HNSC breakdown →