CCNT1

Across TCGA patient cohorts, CCNT1 mutation is significantly associated with the RNA expression of many other genes, with 1,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNT1-associated genes across cancer lineages are RNY4P23, OR5AL2P, and MIR6129. Each is linked with CCNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNT1-to-partner and partner-to-CCNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P23 grouped by CCNT1-low versus CCNT1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT1→partner) and Y-score (partner→CCNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNY4P23 →	+0.389	+4.098	.001	.004	3	3
SKCM	OR5AL2P →	+0.015	+4.640	<.001	.003	3	3
SKCM	MIR6129 →	+0.271	+2.335	.005	.008	3	2
UCEC	WHAMM →	+0.611	+2.839	<.001	.001	3	2
UCEC	DONSON →	+0.458	+2.593	.006	.006	3	2
UCEC	KIAA1522 →	+0.580	+2.523	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,176 associations by consensus.

RNY4P23 by CCNT1 expression — BRCA

Explore this box plot interactively →