CCDC107

Across TCGA patient cohorts, CCDC107 mutation is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC107-associated genes across cancer lineages are SNORD82, RN7SL402P, and EXOC5P1. Each is linked with CCDC107 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC107-to-partner and partner-to-CCDC107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD82 grouped by CCDC107-low versus CCDC107-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC107→partner) and Y-score (partner→CCDC107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD82 →	+0.695	+2.776	<.001	.005	3	2
UCEC	RN7SL402P →	+0.347	+3.546	<.001	<.001	3	2
UCEC	EXOC5P1 →	+0.199	+3.875	<.001	.001	3	1
UCEC	KRTAP21-1 →	+0.095	+3.242	<.001	.007	3	1
UCEC	RNU6-222P →	+0.510	+2.902	<.001	.006	3	1
UCEC	RNU4-58P →	+0.324	+3.133	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

SNORD82 by CCDC107 expression — UCEC

Explore this box plot interactively →