Q-omics provides the consensus-scored SNORD82 profile across patient tissues and cancer cell-line models. SNORD82 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, SNORD82 is differentially expressed in 3, with the highest sampling consensus in COAD. Additionally, SNORD82 RNA expression shows 7,603 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight ACC, COAD, and LSCC as cancer lineages where SNORD82 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD82 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD82 survival associations across molecular data types. SNORD82 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD82 RNA expression–survival associations across cancer types. High SNORD82 expression shows unfavorable associations in ACC, COAD, KIRP, LUAD, UVM and PAAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for SNORD82 RNA expression.
This table summarizes SNORD82 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD82. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD82 shows lower tumor expression in THCA and higher tumor expression in COAD and CHOL. The COAD box plot shows higher SNORD82 RNA expression in tumor versus normal tissue (log2 FC = +0.445, t-test p = .007).
This table shows molecular features associated with SNORD82 in patient tissues and cancer cell lines. In patient samples, SNORD82 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
