CCDC107

Across TCGA pan-cancer cohorts, CCDC107 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CCDC107 data layer compared with 1 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CCDC107 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC107 expression acts as an unfavorable survival marker, although some lineages such as THYM and SARC show a favorable association.

UVM, ACC, and LUSC are the cancer types where CCDC107 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.279	0.810	<.001	102	view →
ACC	DFS	Median	All	0.214	0.702	<.001	96	view →
LUSC	DFS	Quartile	II,III,IV	0.498	0.737	<.001	75	view →
CESC	OS	Tertile	II,III,IV	0.719	0.950	.002	42	view →
LGG	DFS	Median	All	0.672	0.801	<.001	31	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	18	view →
THYM	OS	Median	All	0.965	0.765	.006	16	view →
PRAD	DFS	Tertile	All	0.837	0.929	.006	16	view →
SARC	OS	Tertile	All	0.632	0.380	.002	13	view →
DLBC	OS	Quartile	All	1.000	0.713	.013	13	view →
OV	OS	Quartile	IV	0.819	0.345	<.001	12	view →
READ	OS	Quartile	III,IV	0.262	0.833	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CCDC107–UVM (DFS)

Open the UVM breakdown →