CCDC107

Across TCGA pan-cancer cohorts, CCDC107 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CCDC107’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC107 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC107 is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.

KIRC, LIHC, and HNSC are the cancer types where CCDC107 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC107 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.719	<.001	11	view →
LIHC	Female	All	+1.535	<.001	9	view →
HNSC	All	III,IV	+0.537	.001	8	view →
BLCA	All	III,IV	−0.864	.004	7	view →
LUSC	Female	All	−0.807	<.001	7	view →
COAD	All	II,III,IV	−0.424	<.001	7	view →
BRCA	All	II,III,IV	−0.857	<.001	6	view →
KICH	All	All	−0.608	<.001	6	view →
UCEC	All	III,IV	−0.893	.029	4	view →
LUAD	All	III,IV	−0.298	.015	3	view →
READ	Female	All	−1.032	.003	2	view →
CHOL	All	All	+0.876	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CCDC107–KIRC

Open the KIRC breakdown →