Q-omics provides the consensus-scored CALM2P4 profile across patient tissues and cancer cell-line models. CALM2P4 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, CALM2P4 is differentially expressed in 6, with the highest sampling consensus in COAD. Additionally, CALM2P4 RNA expression shows 7,923 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight THYM, COAD, and ACC as cancer lineages where CALM2P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CALM2P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CALM2P4 survival associations across molecular data types. CALM2P4 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CALM2P4 RNA expression–survival associations across cancer types. High CALM2P4 expression shows unfavorable associations in THYM, ACC, ESCA and READ, but favorable associations in MESO and KIRP. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .013). Together, the overview and detailed table identify THYM as the clearest survival context for CALM2P4 RNA expression.
This table summarizes CALM2P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for CALM2P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CALM2P4 shows lower tumor expression in KIRP and higher tumor expression in COAD, BRCA, HNSC, ESCA and PRAD. The COAD box plot shows higher CALM2P4 RNA expression in tumor versus normal tissue (log2 FC = +0.906, t-test p < 0.001).
This table shows molecular features associated with CALM2P4 in patient tissues and cancer cell lines. In patient samples, CALM2P4 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
