CABYR

Across TCGA patient cohorts, CABYR mutation is significantly associated with the RNA expression of many other genes, with 1,392 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABYR-associated genes across cancer lineages are RNA5SP412, RNA5SP93, and RN7SKP214. Each is linked with CABYR in more than 1 cancer types. Because this analysis shows association rather than direction, both CABYR-to-partner and partner-to-CABYR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by CABYR-low versus CABYR-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABYR→partner) and Y-score (partner→CABYR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.431	+2.074	.004	.004	3	2
COAD	RNA5SP93 →	+0.779	+5.409	<.001	.001	3	2
COAD	RN7SKP214 →	+0.834	+4.734	<.001	<.001	3	2
COAD	TRAJ40 →	+1.039	+4.207	<.001	.001	3	2
COAD	RN7SL442P →	+0.414	+3.843	<.001	.004	3	2
COAD	RN7SL714P →	+0.377	+5.142	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,392 associations by consensus.

RNA5SP412 by CABYR expression — UCEC

Explore this box plot interactively →