CABYR

Across TCGA pan-cancer cohorts, CABYR RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CABYR data layer compared with 6 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher CABYR RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CABYR expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCEC show a favorable association.

MESO, UVM, and KIRC are the cancer types where CABYR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.258	0.508	<.001	108	view →
UVM	OS	Median	All	0.373	0.890	<.001	105	view →
KIRC	DFS	Median	IV	0.436	0.783	<.001	99	view →
LIHC	OS	Tertile	All	0.637	0.851	<.001	68	view →
ACC	DFS	Tertile	All	0.177	0.683	<.001	61	view →
HNSC	OS	Tertile	All	0.429	0.758	<.001	42	view →
STAD	OS	Tertile	All	0.603	0.863	.003	42	view →
BRCA	OS	Median	IV	0.817	0.317	<.001	40	view →
SKCM	DFS	Median	IV	0.176	0.625	.015	17	view →
UCEC	OS	Quartile	IV	0.783	0.393	.027	16	view →
THCA	DFS	Tertile	All	0.955	0.611	.001	14	view →
KICH	OS	Quartile	All	0.795	1.000	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CABYR–MESO (OS)

Open the MESO breakdown →