CABYR

Across TCGA pan-cancer cohorts, CABYR RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CABYR’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CABYR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CABYR is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where CABYR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CABYR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.458	<.001	10	view →
LUAD	Male	All	+2.639	<.001	9	view →
LUSC	Male	II,III,IV	+2.545	<.001	9	view →
HNSC	Male	III,IV	+1.321	<.001	9	view →
KIRP	All	All	+0.670	<.001	9	view →
COAD	Male	II,III,IV	+0.470	<.001	8	view →
LIHC	Male	All	+1.454	<.001	7	view →
UCEC	All	II,III,IV	+1.486	<.001	6	view →
BRCA	All	All	+0.741	<.001	6	view →
BLCA	Female	All	+2.200	.021	4	view →
CHOL	All	All	+1.781	.004	3	view →
THCA	All	All	+0.306	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CABYR–KIRC

Open the KIRC breakdown →