C3P1

Across TCGA patient cohorts, C3P1 mutation is significantly associated with the RNA expression of many other genes, with 2,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3P1-associated genes across cancer lineages are CYCSP27, ZNHIT3, and RN7SL248P. Each is linked with C3P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3P1-to-partner and partner-to-C3P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP27 grouped by C3P1-low versus C3P1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3P1→partner) and Y-score (partner→C3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CYCSP27 →	+0.228	+5.447	<.001	.005	3	2
UCEC	ZNHIT3 →	+0.441	+2.981	.001	<.001	3	2
UCEC	RN7SL248P →	+0.049	+2.915	<.001	.007	3	2
UCEC	CRYBB2P1 →	+0.712	+3.480	<.001	<.001	3	2
SKCM	CGRRF1 →	+0.522	+3.472	.004	.002	3	2
UCEC	KIAA0586 →	+0.393	+2.839	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,679 associations by consensus.

CYCSP27 by C3P1 expression — LIHC

Explore this box plot interactively →