C3P1

Across TCGA pan-cancer cohorts, C3P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated C3P1 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C3P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C3P1 expression acts as an unfavorable survival marker, although some lineages such as LIHC and COAD show a favorable association.

KIRC, ACC, and LIHC are the cancer types where C3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.532	0.716	<.001	166	view →
ACC	DFS	Median	All	0.249	0.652	<.001	78	view →
LIHC	OS	Quartile	All	0.870	0.685	<.001	48	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	45	view →
KIRP	OS	Median	All	0.524	0.780	<.001	41	view →
MESO	DFS	Tertile	III,IV	0.172	0.403	.009	36	view →
CHOL	OS	Quartile	II,III,IV	0.111	1.000	.002	33	view →
ESCA	OS	Quartile	All	0.323	1.000	.003	24	view →
STAD	DFS	Tertile	All	0.234	0.432	.031	17	view →
COAD	OS	Median	III,IV	0.893	0.691	.005	17	view →
READ	OS	Median	III,IV	0.812	1.000	.007	17	view →
CESC	OS	Tertile	II,III,IV	0.671	0.857	.005	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

C3P1–KIRC (DFS)

Open the KIRC breakdown →