C3P1

Across TCGA pan-cancer cohorts, C3P1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of C3P1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where C3P1 RNA is repressed in tumor relative to normal tissue. In most cancer types C3P1 is over-expressed in tumor, although a few such as LIHC and KICH show the opposite, repressed pattern.

LIHC, KICH, and CHOL are the cancer types where C3P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C3P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	−3.614	<.001	8	view →
KICH	All	All	−0.301	<.001	6	view →
CHOL	Female	All	−6.026	<.001	5	view →
STAD	All	All	+0.499	.002	4	view →
COAD	All	All	+0.129	.001	4	view →
LUAD	Female	All	+0.013	.002	4	view →
KIRP	Female	II,III,IV	+0.144	.015	2	view →
KIRC	Male	All	−0.064	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

C3P1–LIHC

Open the LIHC breakdown →