C15orf65

Across TCGA patient cohorts, C15orf65 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C15orf65-associated genes across cancer lineages are H3P46, RBMY2KP, and PRYP5. Each is linked with C15orf65 in more than 1 cancer types. Because this analysis shows association rather than direction, both C15orf65-to-partner and partner-to-C15orf65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3P46 grouped by C15orf65-low versus C15orf65-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf65→partner) and Y-score (partner→C15orf65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	H3P46 →	+0.193	+7.731	<.001	.009	3	1
BRCA	RBMY2KP →	+0.064	+8.055	<.001	.007	3	1
BRCA	PRYP5 →	+0.174	+9.057	<.001	.003	3	1
BRCA	MIR3689D2 →	+0.552	+8.055	<.001	.007	3	1
UCEC	USP9YP2 →	+0.054	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

H3P46 by C15orf65 expression — BRCA

Explore this box plot interactively →